Research Data

ESTRO-ALL Combination Natural Progesterone Cream
With Three Plant Derived Estrogens For Menopausal Women

Defining natural estrogen can be tricky, as the phrase can be used to refer to one of four substances.

What are Endogenous Estrogens?
Endogenous estrogens are hormones manufactured in our bodies

• Estradiol- Principal estrogen before menopause
• Estrone- Main estrogen present after menopause, created from androstenedione by body fat
• Estriol- A weaker and safer estrogen created when estradiol and estrone are metabolized in the body

Phytoestrogens
Sarati uses many plant sources, primarily soy, wild yam, black cohosh, chasteberry, and red clover in ESTRO-ALL Our transdermal formulation delivers about 1 mg of natural estrogens, together with 20 mg of progesterone. Phyto-estrogens are not as strong as the other types of estrogens, but studies have been conducted that demonstrate that this combination may be the safest and most effective form of estrogen for women. Another advantage of the combination progesterone/estrogen cream is with the combination, one is able to gain the benefits of natural progesterone, such as improving memory, enhancing energy, stimulating the thyroid, elevating mood and reducing the risk of breast cancer. NE Journal of Med.Vol. 332, June 15, 95, Number 24.

Another advantage of the combination progesterone/estrogen cream is with the combination, one is able to gain the benefits of natural progesterone, such as improving memory, enhancing energy, stimulating the thyroid, elevating mood and reducing the risk of breast cancer.
NE Journal of Med.Vol. 332, June 15, 95, Number 24.

What is the advantage of transdermal absortion?
If one takes Remifemin, or other herbal remedies, such as black cohosh, chasteberry or red clover, in either a Prominsil capsules or using drops, the liver destroys up 80% of the active estrogenic sterols.

Estro-all contains 960 mg. of U. S. P. grade natural progesterone cream. A recent study conducted in France, focused on the effect of progesterone and estradiol on human breast cancer in vivo. The findings can be found in "Influences of percutaneous administration of estradiol and progesterone on human breast epithelial cell cycle in vivo " Fertility and Sterility l995; 63:785-791.

40 premenopausal women undergoing breast surgery agreed to volunteer for this study to see the effect of E2 (Estradiol) and P (Progesterone) on the epithelial cell cycle of normal human breast in vivo. The results showed increased E2 increases the number of cycling epithelial cells, increase P significantly decreases the number of cycling epithelial cells. Increase E2 levels increase breast cell proliferation, a recognized cancer risk factor. Physiologic doses of transdermal progesterone prevent E2-induced breast cell proliferation to normal levels.

Transdermal progesterone administered monthly will reduce risk of breast cancer. Summary of findings from Dr. John R. Lee, MD, October 9, 1995.

Research is badly need on phytoestrogens and estrogen metabolism. There has not been one, controlled, long-term study of the use of natural estrogens as replacement therapy for women by the pharmaceutical/medical community. Without this kind of study, the best we can say is we don't know anything clinical, but rely on research provided by the well-studied black cohosh. We have evidence based on results from thousands of women who testify on their results from all of our formulations.

Premarin is one of the most popular forms of estrogen prescribed for menopausal and postmenopausal women, and it is considered a natural estrogen because it is extracted from the urine of pregnant mares. We maintain it is only "natural" for horses, not humans.

We've wasted 40 years studying horse hormones in humans. What the future holds for new studies is more of the same, and little choice, because, unfortunately, the NIH Study is only evaluating Premarin and Provera. These results will not be released until year 2007, so in the meantime, try our transdermal, safe, proven, formulations.

Sarati International Inc. is a wholesale manufacturer of proprietary formulations for private label products. To order Estro-All.

Sarati does not practice medicine or diagnose, nor do we offer a cure for the physical conditions of PMS or Menopause. We offer a transdermal approach for those millions of women who are unable or unwilling to use the traditional treatment with conjugated estrogens, and synthetic progestins. Alternative does not imply lower standard, it only offers a choice.

TEN IMPORTANT REASONS TO DISTRIBUTE ESTRO-ALL
A NATURAL TRI-PHYTO-ESTROGEN / PROGESTERONE CREAM

1. ABSOLUTELY NO OVER-THE-COUNTER COMPETITION.
2. INCREDIBLE BABY - BOOMER DEMAND
3. CONSUMABLE PRODUCT
4. REGULAR REPEAT MONTHLY CUSTOMERS
5. UNPARALLELED CUSTOMER LOYALTY TO PRODUCT
6. UNIQUE NATURAL FORMULATION
7. ALTERNATIVE SOLUTION FOR MENOPAUSAL WOMEN
8. SAFE, FAST, AND EFFECTIVE FORMULA
9. ATTRACTIVE AND CONVENIENT PACKAGING
10. PRICED TO BE AFFORDABLE FOR ALL WOMEN.

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